In recent development of novel drug delivery system it is observed that amongst the various natural polymers one of the most deserving polymers for various drug delivery systems is gellan gum. Gellan gum is repeating unit of the polymer is a tetrasaccharide, which consists of two residues of D-glucose and one of each residue of L-rhamnose and D-glucuronic acid. Gellan gum, originally a food ingredient, has been used to develop novel pharmaceutical formulation; it can be used in nasal drug delivery, ophthalmic drug delivery, in situ gel formulation, tablet excipient. Gellan gum is used primarily as a gelling agent, alternative to agar, in microbiological culture. Various significant works has been carried out in combination with other polymer to develop sustained and targeted formulation. On Gellan gum various new works are being carried out to develop new derivatives.
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